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07-15-2011 15:06
’Super’ gonorrhea strain resistant to all antibiotics  src=http://img.koreatimes.co.kr/upload/news/110715_pm_Super.jpg
Gonorrhea, the world’s most common se-xually transmitted disease (STD), has re-surfaced with vengeance, even more bulletproof to antibiotics than before. A new strain - dubbed H041- resistant to all currently available antibiotics, has been discovered in Japan. 

The discovery was presented by Dr. Magnus Unemo, Dr. Makoto Ohnishi, and colleagues on July 11 at a conference in Quebec City, Canada. 

“This is both an alarming and predictable discovery,” said Dr. Unemo of the Swedish Reference Laboratory for Pathogenic Neisseria in a statement. 

Multi-drug resistance is “predictable” because most strains of Neisseria gonorrhoeae, the bacterial organism that causes gonorrhea, are resistant to at least one type of antibiotics. When exposed to them, only the “fittest” of bacteria with stronger resistance survive and are able to pass on their robust genes to their offspring - equally equipped with antibiotic-resistance. This “survival of the fittest”, in naturalist Charles Darwin’s words, eventually creates a strain with solid resistance to certain antibiotics. 

Today, H041 is seen as an “alarming” threat to global health, seeing that there are no alternative drugs in the pharmaceutical pipeline. “U.S. gonorrhea control strategy relies upon effective antibiotic therapy, the CDC claimed on Friday. No other well-studied and effective antibiotic treatment options or combinations currently are available.

According to a report released by Centers for Disease Control (CDC) on July 8, what once used to be an easily treatable infection now responds feebly to Cephalospirins - the last remaining class of antibiotic still effective. Others such as penicillin and tetracycline have been obsolete since the 1970s. 

One of the biggest concerns is that the super strain will not only evolve, but also spread. 700,000 new cases of Gonorrhea are reported each year in United States. As commonplace as it is, gonorrhea may bring physical damage to patients if it forces new, costly methods of treatment. 

Left untreated, patients may suffer from scarring of the reproductive tract, and in women, lifelong infertility, or pelvic inflammatory disease. 
While it is still too early to assess if this new strain [from Japan] has become widespread, the history of newly emergent resistance in the bacterium suggests that it may spread rapidly unless new drugs and effective treatment programs are developed, Unemo commented.







日 スーパー淋疾菌発見, 世界保健非常

どんな抗生剤も聞かない ¥"スーパー淋疾菌¥"が日本で発見された. 淋疾は一番有り勝ちに発生する性病中の一つのうえ今度発見された淋疾菌は常に制に対する耐性が強くて世界保健に非常事態になった.

がスーパーバグはスウェーデンのマグヌスウネモによって日本京都で採取されたサンプルで初めて発見された. 性燭を通じて伝染する H041と呼ばれるこのスーパーバグ淋疾菌は淋疾菌治療に唯一に效果を現わしているセファロスポリン級ハングセングゼエさえ完璧な抵抗力を取り揃えたことで現われてどんな治療剤でも退治されないことと知られた.

ウネモは去る 1840年代淋疾治療に抗生剤が初めて使われ始めた以後淋疾菌バクテリアは淋疾治療剤に対する抵抗力をおびただしく進めたと鳥 ¥"スーパーバグ¥" 淋疾菌が 10〜20年の間に全世界で拡散する危険が大きいと言った. 彼は 11日カナダクェベックで開かれる国際性病研究協会(ISSTDR) 会議でこの淋疾菌スーパーバグを報告する予定だ.

去年香港と中国などアジア地域で抗生剤に耐性を取り揃えた変種淋疾菌たちが発見されるによってすべての抗生剤が要らない ¥"スーパーバグ¥" 淋疾菌の登場可能性がイギリス科学者たちによってもう提示された. ここにウネモは 日本は過去から治療剤に耐性を取り揃えた多くの淋疾菌変種たちが最初に発見されて全世界で拡散した発源地と言いながら 日本でスーパーバグ淋疾菌が初めて発見されたことは驚きべきではないと付け加えた.

淋疾はソングゾブチォックによって伝染する性病で治療しないで捨ておく場合骨盤感染による疾病と女性の理想姙娠, 不妊などをもたらす.

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07-15-2011 15:06
’Super’ gonorrhea strain resistant to all antibiotics 
Gonorrhea, the world’s most common se-xually transmitted disease (STD), has re-surfaced with vengeance, even more bulletproof to antibiotics than before. A new strain - dubbed H041- resistant to all currently available antibiotics, has been discovered in Japan. 

The discovery was presented by Dr. Magnus Unemo, Dr. Makoto Ohnishi, and colleagues on July 11 at a conference in Quebec City, Canada. 

“This is both an alarming and predictable discovery,” said Dr. Unemo of the Swedish Reference Laboratory for Pathogenic Neisseria in a statement. 

Multi-drug resistance is “predictable” because most strains of Neisseria gonorrhoeae, the bacterial organism that causes gonorrhea, are resistant to at least one type of antibiotics. When exposed to them, only the “fittest” of bacteria with stronger resistance survive and are able to pass on their robust genes to their offspring - equally equipped with antibiotic-resistance. This “survival of the fittest”, in naturalist Charles Darwin’s words, eventually creates a strain with solid resistance to certain antibiotics. 

Today, H041 is seen as an “alarming” threat to global health, seeing that there are no alternative drugs in the pharmaceutical pipeline. “U.S. gonorrhea control strategy relies upon effective antibiotic therapy," the CDC claimed on Friday. "No other well-studied and effective antibiotic treatment options or combinations currently are available."

According to a report released by Centers for Disease Control (CDC) on July 8, what once used to be an easily treatable infection now responds feebly to Cephalospirins - the last remaining class of antibiotic still effective. Others such as penicillin and tetracycline have been obsolete since the 1970s. 

One of the biggest concerns is that the super strain will not only evolve, but also spread. 700,000 new cases of Gonorrhea are reported each year in United States. As commonplace as it is, gonorrhea may bring physical damage to patients if it forces new, costly methods of treatment. 

Left untreated, patients may suffer from scarring of the reproductive tract, and in women, lifelong infertility, or pelvic inflammatory disease. 
"While it is still too early to assess if this new strain [from Japan] has become widespread, the history of newly emergent resistance in the bacterium suggests that it may spread rapidly unless new drugs and effective treatment programs are developed," Unemo commented.







日 슈퍼 임질균 발견, 세계 보건 비상

어떠한 항생제도 듣지 않는 "슈퍼 임질균"이 일본에서 발견됐다. 임질은 가장 흔하게 발생하는 성병 중 하나인데다 이번에 발견된 임질균은 항상제에 대한 내성이 강해 세계 보건에 비상이 걸렸다.

이 슈퍼버그는 스웨덴의 마그누스 우네모에 의해 일본 교토에서 채취된 샘플에서 처음 발견되었다. 성 촉을 통해 전염되는 H041로 불리는 이 슈퍼버그 임질균은 임질균 치료에 유일하게 효과를 나타내고 있는 세팔로스포린급 항생제에마저 완벽한 저항력을 갖춘 것으로 나타나 어떤 치료제로도 퇴치되지 않는 것으로 알려졌다.

우네모는 "지난 1840년대 임질 치료에 항생제가 처음 사용되기 시작한 이후 임질균 박테리아는 임질 치료제에 대한 저항력을 엄청나게 향상시켰다"며 새 "슈퍼버그" 임질균이 10∼20년 사이에 전세계로 확산될 위험이 크다고 말했다. 그는 11일 캐나다 퀘벡에서 열리는 국제성병연구협회(ISSTDR) 회의에서 이 임질균 슈퍼버그를 보고할 예정이다.

지난해 홍콩과 중국 등 아시아 지역에서 항생제에 내성을 갖춘 변종 임질균들이 발견됨에 따라 모든 항생제가 소용없는 "슈퍼버그" 임질균의 등장 가능성이 영국 과학자들에 의해 이미 제시되었다. 이에 우네모는 "일본은 과거부터 치료제에 내성을 갖춘 여러 임질균 변종들이 최초로 발견돼 전 세계로 확산된 발원지"라며 "일본에서 슈퍼버그 임질균이 처음 발견된 것은 놀라운 일이 아니다"라고 덧붙였다.

임질은 성접촉에 의해 전염되는 성병으로 치료하지 않고 방치할 경우 골반 감염에 따른 질병과 여성의 이상 임신, 불임 등을 초래한다.

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